Prototype 2 continues the shape-shifting, open-world action franchise, this time focusing on Sgt. James Heller and his mission to destroy Prototype's original anti-hero, Alex Mercer. In the place of tyrant three-year-olds, Prototype 2 has a tyrant army man, a generic vessel of scowls and death called James Heller. Heller is exceedingly cross because Alex Mercer – anti-hero of the first, flawed Prototype game – has caused the death of his wife and daughter, and rather than submitting to a good revenge-knifing has infected Heller with the same Cronenbergian virus that previously caused Mercer to grow giant claws and murder half of New York. With Mercer in the wild like some ultra-hoody from Middle England's nightmares, Heller clenches an ominously rippling fist and determines to uncover the truth behind the virus, and murder the other half of New York.